Isseroff Lab - UC Davis
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Hypoxic preconditioning of mesenchymal stromal cells induces metabolic changes, enhances survival, and promotes cell ret...

Beegle, Julie Lakatos, Kinga Kalomoiris, Stefanos Stewart, Heather Isseroff, R Rivkah Nolta, Jan A Fierro, Fernando A

Published in Stem cells (Dayton, Ohio)

Mesenchymal stem cells/multipotent stromal cells (MSCs) are promising therapeutics for a variety of conditions. However, after transplantation, cell retention remains extremely challenging. Given that many hypoxic signals are transitory and that the therapeutic administration of MSCs is typically into tissues that are normally hypoxic, we studied t...

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