Kim, Min-Ho Gorouhi, Farzam Ramirez, Sandra Granick, Jennifer L Byrne, Barbara A Soulika, Athena M Simon, Scott I Isseroff, Rivkah R
Published in
The Journal of investigative dermatology
Stress-induced hormones can alter the inflammatory response to tissue injury; however, the precise mechanism by which epinephrine influences inflammatory response and wound healing is not well defined. Here we demonstrate that epinephrine alters the neutrophil (polymorphonuclear leukocyte (PMN))-dependent inflammatory response to a cutaneous wound....
Sivamani, Raja K Shi, Biao Griffiths, Elizabeth Vu, Shirley M Lev-Tov, Hadar A Dahle, Sara Chigbrow, Marianne La, Thi Dinh Mashburn, Chelcy Peavy, Thomas R
...
Published in
The Journal of investigative dermatology
Keratinocyte migration is critical for wound re-epithelialization. Previous studies showed that epinephrine activates the beta2-adrenergic receptor (B2AR), impairing keratinocyte migration. Here, we investigated the keratinocyte catecholamine synthetic pathway in response to acute trauma. Cultured keratinocytes were scratch wounded and expression l...
